GHRP-2 (5 mg) x 5 vials

$60.00

GHRP-2 (5 mg) x 5 vials

Stimulation of GH secretion. Appetite promotion. Fat mass decrease. Muscle mass increase. Lowering of cholesterol level. Skin and bones state improvement.

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SKU: GHRP-2 Category: Tags: ,

Description

GHRP-2

Amino acid sequence: D-Ala-D-β-Nal-Ala-Trp-D-Phe-Lys-NH2 Formula: C45H55N9O6 Mol. Mass: 817.9 g/mol Half-life: Between 15 and 60 minutes

Appearance:

Sterile Filtered White lyophilized (freeze-dried) powder. Growth hormone releasing peptide (GHRP-2) is the most potent of the GH secretagogues.

Growth hormone secretagogues stimulate the anterior pituitary gland causing an increase in GH release. This was demonstrated in an early study, GHRP-2 (also known as KP-102) was tested on adult male rats: KP-102 induced a large plasma GH response at a dose of 0.5 micrograms/kg BW in conscious rats, although GH-releasing abilities of KP-102 varied markedly depending on the phase of GH secretion.

It produced a large plasma GH response in the presence of exogenous GH-releasing factor (GRF). During intermittent administration of GRF, the somatotropes became refractory to a large bolus dose of GRF, but KP-102 induced a marked increase of plasma GH. KP-102 and GRF acted synergistically on GH secretion in control animals.

Taken together, these findings suggest that the KP-102-induced GH secretion largely depends on GRF and the secretagogue potentiates the GRF effect by antagonizing the SS action at the level of somatotropes.

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